Dihydroorotate Dehydrogenase (Quinone), Mitochondrial

Preferred Label : Dihydroorotate Dehydrogenase (Quinone), Mitochondrial;

NCIt synonyms : DHODH; (S)-dihydroorotate:oxygen oxidoreductase; DHOdehase; Dihydroorotic Acid Dehydrogenase; EC 1.3.3.1; Dihydroorotate Oxidase; Dihydroorotate Dehydrogenase;

NCIt definition : Dihydroorotate dehydrogenase (quinone), mitochondrial (395 aa, 43 kDa) is encoded by the human DHODH gene. This protein plays a role in the biosynthesis of pyrimidines.;

Details

Origin ID

C17289;

UMLS CUI

C3887697;

Currated CISMeF NLP mapping
- Dihydroorotate Dehydrogenase [MeSH concept]
- Dihydroorotate Dehydrogenase [MeSH Descriptor]
- Dihydroorotate dehydrogenase (substance) [SNOMED CT concept]
- Dihydroorotate oxidase (substance) [SNOMED CT concept]
- dihydroorotate dehydrogenase [MeSH concept]
- dihydroorotate dehydrogenase [SNOMED Notion]
- dihydroorotate oxidase [MeSH Descriptor]
- dihydroorotate oxidase [MeSH concept]
- dihydroorotate oxidase [SNOMED Notion]
OMIM relation
- Dihydroorotate dehydrogenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DHODH Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Inner Mitochondrial Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- DHODH Inhibitor JBZ-001 [NCIt concept]
- DHODH Inhibitor JNJ-74856665 [NCIt concept]
- DHODH Inhibitor RP7214 [NCIt concept]
- Dihydroorotate Dehydrogenase Inhibitor AG-636 [NCIt concept]
- Farudodstat [NCIt concept]
- Leflunomide [NCIt concept]
- Orludodstat [NCIt concept]

Keyword's position in hierarchy(ies) :

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