Dihydroorotate Dehydrogenase

Preferred Label : Dihydroorotate Dehydrogenase;

MeSH definition : An oxidoreductase that catalyzes the conversion of DIHYDROOROTATE to orotate with QUINONE as an electron acceptor in the biosynthesis of PYRIMIDINES.;

MeSH synonym : Dehydrogenase, Dihydroorotate; Dihydro-Orotate Dehydrogenase; Dehydrogenase, Dihydro-Orotate; DHODH;

MeSH hyponym : DHODase B; B, DHODase; Oxidoreductase, Dihydroorotate-Ubiquinone; DHOO-Dehydrogenase-U; DHOO Dehydrogenase U; Dihydroorotate Dehydrogenase (Ubiquinone); Dihydro-Orotate-Cytochrome C Reductase; C Reductase, Dihydro-Orotate-Cytochrome; Dihydro Orotate Cytochrome C Reductase; Reductase, Dihydro-Orotate-Cytochrome C; DHODase A; A, DHODase;

MeSH Related Number : EC 1.3.5-; EC 1.3.5.2;

Details

Origin ID

D000090722;

UMLS CUI

C0058099;

ATC code(s)
- Dihydroorotate dehydrogenase (DHODH) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DHODH Gene [NCIt concept]
- dihydroorotate dehydrogenase (quinone) [ORDO Gene]
Currated CISMeF NLP mapping
- Dihydroorotate Dehydrogenase (Quinone), Mitochondrial [NCIt concept]
- Dihydroorotate dehydrogenase (substance) [SNOMED CT concept]
- dihydroorotate dehydrogenase [SNOMED Notion]
Record concept(s)
- Dihydroorotate Dehydrogenase [MeSH concept]
- dihydroorotate dehydrogenase type A [MeSH concept]
- dihydroorotate dehydrogenase type B [MeSH concept]
- dihydroorotate dehydrogenase type C [MeSH concept]
- dihydroorotate-ubiquinone oxidoreductase [MeSH concept]
See also inter- (CISMeF)
- Dihydroorotate dehydrogenase [OMIM gene]
- Dihydroorotate oxidase (substance) [SNOMED CT concept]
- dihydroorotate oxidase [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Dihydroorotate dehydrogenase (substance) [SNOMED CT concept]
- dihydroorotate dehydrogenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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