Lysine-Specific Histone Demethylase 1A

Preferred Label : Lysine-Specific Histone Demethylase 1A;

NCIt synonyms : Flavin-Containing Amine Oxidase Domain-Containing Protein 2; BRAF35-HDAC Complex Protein BHC110; FAD-Binding Protein BRAF35-HDAC Complex, 110 kDa Subunit; Lysine-Specific Histone Demethylase 1; KDM1A; [Histone H3]-Dimethyl-L-Lysine(4) FAD-Dependent Demethylase 1A; LSD1; Lysine-Specific Demethylase 1; EC 1.14.99.66; Lysine Demethylase 1A; Lysine-Specific Demethylase 1A;

NCIt definition : Lysine-specific histone demethylase 1A (852 aa, 93 kDa) is encoded by the human KDM1A gene. This protein is involved in both histone demethylation and transcriptional regulation.;

Détails

Origin ID

C78143;

UMLS CUI

C1531135;

OMIM relation
- Lysine demethylase 1a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KDM1A protein, human [MeSH concept]
- KDM1A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KDM1A Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Histone Demethylation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Bomedemstat [NCIt concept]
- Bomedemstat Tosylate [NCIt concept]
- Iadademstat [NCIt concept]
- LSD1 Inhibitor GSK2879552 [NCIt concept]
- LSD1 Inhibitor SYHA1807 [NCIt concept]
- LSD1 Inhibitor TAS1440 [NCIt concept]
- LSD1/HDAC6 Inhibitor JBI-802 [NCIt concept]
- Lysine-specific Demethylase 1 Inhibitor INCB059872 [NCIt concept]
- Pulrodemstat [NCIt concept]
- Seclidemstat [NCIt concept]
- Seclidemstat Mesylate [NCIt concept]
- Tranylcypromine [NCIt concept]
- Tranylcypromine Sulfate [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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