Polycomb Protein SUZ12

Preferred Label : Polycomb Protein SUZ12;

NCIt synonyms : Suppressor of Zeste 12 Protein Homolog; Chet 9 Protein; Joined To JAZF1 Protein; Chromatin Precipitated E2F Target 9 Protein; SUZ12;

NCIt definition : Polycomb protein SUZ12 (739 aa, 83 kDa) is encoded by the human SUZ12 gene. This protein is a histone methyltransferase and plays a critical role in embryonic development.;

NCIt note : Polycomb protein SUZ12 is a component of the polycomb repressor complex 2 complex which plays a role in the repression of homeotic genes during embryonic development. (SwissProt);

Details

Origin ID

C73547;

UMLS CUI

C2347620;

OMIM relation
- Suz12 polycomb repressive complex 2 subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- SUZ12 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
- Polycomb-Group Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Polycomb Repressive Complex 2 [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Embryogenesis [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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