E3 Ubiquitin-Protein Ligase CHFR

Preferred Label : E3 Ubiquitin-Protein Ligase CHFR;

NCIt synonyms : Checkpoint with Forkhead and RING Finger Domains Protein; RING Finger Protein 196; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase CHFR (664 aa, 73 kDa) is encoded by the human CHFR gene. This protein is involved in both ubiquitination of proteins and the mitotic checkpoint.;

Details

Origin ID

C77211;

UMLS CUI

C2699835;

OMIM relation
- Checkpoint protein with fha and ring finger domains [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CHFR Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Checkpoint [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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