" /> Trifunctional Enzyme Subunit Alpha, Mitochondrial - CISMeF





Preferred Label : Trifunctional Enzyme Subunit Alpha, Mitochondrial;

NCIt synonyms : TP-Alpha; EC 4.2.1.17/EC 1.1.1.211; Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Alpha; Long-Chain Enoyl-CoA Hydratase/Long Chain 3-Hydroxyacyl-CoA Dehydrogenase; 78 kDa Gastrin-Binding Protein; HADHA; Monolysocardiolipin Acyltransferase;

NCIt definition : Trifunctional enzyme subunit alpha, mitochondrial (763 aa, 83 kDa) is encoded by the human HADHA gene. This protein is involved in the metabolism of long-chain fatty acids.;

NCIt note : The mitochondrial trifunctional enzyme is a heterotetramer composed of 2 alpha (HADHA) and 2 beta (HADHB) subunits.; Trifunctional enzyme subunit alpha, mitochondrial includes two domains. One with long-chain enoyl-CoA hydratase (EC 4.2.1.17) activity and a second with long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211) activity; however, this enzyme may also exhibit monolysocardiolipin acyltransferase (EC 2.3.1.-) activity. (UniProt);

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
28/04/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.