Ubiquitin Carboxyl-Terminal Hydrolase CYLD

Preferred Label : Ubiquitin Carboxyl-Terminal Hydrolase CYLD;

NCIt synonyms : Ubiquitin Thiolesterase CYLD; Ubiquitin-Specific-Processing Protease CYLD; EC 3.4.19.12; Deubiquitinating Enzyme CYLD; CYLD; Ubiquitin Thioesterase CYLD; Ubiquitin Specific Peptidase Like 2; Probable Ubiquitin Carboxyl-Terminal Hydrolase CYLD;

NCIt definition : Ubiquitin carboxyl-terminal hydrolase CYLD (956 aa, 107 kDa) is encoded by the human CYLD gene. This protein is involved in the mediation of protein deubiquitination and the regulation of the cell cycle.;

Details

Origin ID

C92683;

UMLS CUI

C2985250;

OMIM relation
- Cyld lysine-63 deubiquitinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CYLD protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CYLD Gene [NCIt concept]
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitin C-Terminal Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Cylindroma [NCIt concept]
- Trichoblastoma [NCIt concept]
- Turban Tumor [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Process [NCIt concept]
- Deubiquitination [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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