NCIt definition : Dual-specificity protein phosphatases are a subclass of protein tyrosine phosphatases
that are uniquely able to hydrolyse the phosphate ester bond on both a tyrosine and
a threonine or serine residue on the same protein. Dual-specificity phosphatases have
a central role in the complex regulation of signalling pathways that are involved
in cell stress responses, proliferation and death. (from Nat Rev Drug Discov 2002;1:961-76);