Preferred Label : Protein Tyrosine Phosphatase Gene;
NCIt synonyms : PTP Family Gene;
NCIt definition : Protein Tyrosine Phosphatase Genes encode Protein Tyrosine Phosphatases, enzymes that
specifically remove tyrosine-bound phosphate groups from many phosphoproteins, including
many enzymes phosphorylated by a tyrosine kinase. Together with protein tyrosine kinases,
Tyrosine Phosphatases regulate tyrosine phosphorylation and dephosphorylation in cellular
signal transduction and may play a role in cell growth control and carcinogenesis.
(NCI);