Receptor-Type Tyrosine-Protein Phosphatase R

Preferred Label : Receptor-Type Tyrosine-Protein Phosphatase R;

NCIt synonyms : Receptor Type Protein Tyrosine Phosphatase R; PTPRR; Protein Tyrosine Phosphatase Receptor Type R; PTP-SL; Ch-1PTPase; EC-PTP; PCPTP1; Protein Tyrosine Phosphatase Cr1PTPase; PTPBR7; NC-PTPCOM1; Protein Tyrosine Phosphatase NC-PTPCOM1; R-PTP-R; EC 3.1.3.48; Protein Tyrosine Phosphatase-PCPTP1; Protein-Tyrosine Phosphatase PCPTP1;

NCIt definition : Receptor-type tyrosine-protein phosphatase R (657 aa, 74 kDa) is encoded by the human PTPRR gene. This protein is involved in both protein dephosphorylation and the sequestration of unphosphorylated mitogen-activated protein kinases.;

Details

Origin ID

C37314;

UMLS CUI

C1744370;

Currated CISMeF NLP mapping
- protein tyrosine phosphatase, receptor type R [MeSH concept]
OMIM relation
- Protein-tyrosine phosphatase, receptor-type, r [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PTPRR protein, human [MeSH concept]
- PTPRR protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PTPRR Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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