protein tyrosine phosphatases

Preferred Label : protein tyrosine phosphatases;

MeSH definition : An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.;

MeSH synonym : phosphoprotein phosphatase, tyrosyl; protein phosphatase, phosphotyrosyl; protein-tyrosine phosphatase; ptpase; phosphatases, protein tyrosine; tyrosine phosphatases, protein; phosphotyrosyl protein phosphatase; phosphatase, phosphotyrosyl protein; phosphatase, protein-tyrosine; tyrosyl phosphoprotein phosphatase; phosphatase, tyrosyl phosphoprotein; phosphotyrosine phosphatase; phosphatase, phosphotyrosine; protein-tyrosine-phosphatase; protein tyrosine phosphatase;

MeSH CAS label : protein-tyrosine-phosphate phosphohydrolase;

MeSH Related Number : 79747-53-8 (CAS RN);

Registry Number MeSH : EC 3.1.3.48;

MeSH annotation : general; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Protein-tyrosine-phosphate phosphohydrolase;

Is substance : O;

UNII : EC 3.1.3.48;

Details

Origin ID

D017027;

UMLS CUI

C0085536;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase Inhibitor 3 [NCIt concept]
- Dual Specificity Protein Phosphatase 1 [NCIt concept]
- Dual Specificity Protein Phosphatase 3 [NCIt concept]
- Eyes Absent Homolog 1 [NCIt concept]
- Low Molecular Weight Phosphotyrosine Protein Phosphatase [NCIt concept]
- M-Phase Inducer Phosphatase 1 [NCIt concept]
- PTPRF interacting protein alpha 3 [HGNC gene]
- Protein Tyrosine Phosphatase [NCIt concept]
- Protein-tyrosine-phosphatase (substance) [SNOMED CT concept]
- protein-tyrosine-phosphatase [SNOMED Notion]
Indexing information
- (1,1-difluoro-1-((6-carboxamidoglutamic)naphth-2-yl))methylphosphonic acid [MeSH Supplementary Concept]
- (1,1-difluoro-1-((6-carboxy)naphth-2-yl))methylphosphonic acid [MeSH Supplementary Concept]
- (1,1-difluoro-1-(2-naphthlenyl)methyl)phosphonic acid [MeSH Supplementary Concept]
- 2-((4-methylthiopyridin-2-yl)methylsulfinyl)benzimidazole [MeSH Supplementary Concept]
- 2-(4-((2)-2-(((2)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanoyl)amino)-3-oxo-3-(pentylamino)propyl)-2-(1(2)H-tetrazol-5-yl)phenoxy)acetic acid [MeSH Supplementary Concept]
- 2-(carboxymethoxy)-5-(2-((2-((3-carboxypropanoyl)amino)-3-phenylpropanoyl)amio)-3-oxo-3-(pentylamino)propyl)benzoic acid [MeSH Supplementary Concept]
- 2-(oxalylamino)benzoic acid [MeSH Supplementary Concept]
- 4'-O-(2-(2-fluoromalonyl))tyrosine [MeSH Supplementary Concept]
- 4-(O-nitrofurfuryl N-methyl-N-(4-chlorobutyl) phosphono(difluoromethyl))phenylacetyl-aspartyl-4-(O-nitrofurfuryl N-methyl-N-(4-chlorobutyl) phosphono(difluoromethyl))-N-(9-fluorenylmethoxycarbonyl)-phenylalanine amide [MeSH Supplementary Concept]
- 4-difluoromethylphenyl phosphate [MeSH Supplementary Concept]
- 4-hydroxy-3,3-dimethyl-2H-benzo(g)indole-2,5(3H)-dione [MeSH Supplementary Concept]
- 5-(6-cyano-1-hexen-2-yl)-7a-methyl-1-(6-methylhept-2-yl)hexahydroindan-4-acetic acid [MeSH Supplementary Concept]
- 7-bromo-6-difluoromethylphosphonate 3-naphthalenenitrile [MeSH Supplementary Concept]
- CinnGEL 2Me [MeSH Supplementary Concept]
- RTKI cpd [MeSH Supplementary Concept]
- UA 0713 [MeSH Supplementary Concept]
- bis(4-trifluoromethyl-sulfonamidophenyl)-1,4-diisopropyl-benzene [MeSH Supplementary Concept]
- bis(N,N-dimethylhydroxamido)hydroxooxovanadate [MeSH Supplementary Concept]
- bis(maltolato)oxovanadium(IV) [MeSH Supplementary Concept]
- bisperoxo(1,10-phenanthroline)oxovanadate(1-) [MeSH Supplementary Concept]
- brunsvicamide A [MeSH Supplementary Concept]
- brunsvicamide B [MeSH Supplementary Concept]
- brunsvicamide C [MeSH Supplementary Concept]
- chloro(diphenyl-2-pyridylphosphine)gold(I) [MeSH Supplementary Concept]
- dephostatin [MeSH Supplementary Concept]
- dihydrocarolic acid [MeSH Supplementary Concept]
- dysidiolide [MeSH Supplementary Concept]
- nocardione A [MeSH Supplementary Concept]
- oxodiperoxo(1,10-phenanthroline)vanadate(V) [MeSH Supplementary Concept]
- penitricin D [MeSH Supplementary Concept]
- permolybdate [MeSH Supplementary Concept]
- peroxyvanadate [MeSH Supplementary Concept]
- pervanadate [MeSH Supplementary Concept]
- phenylhydrazonopyrazolone sulfonate 1 [MeSH Supplementary Concept]
- phosphatoquinone A [MeSH Supplementary Concept]
- phosphatoquinone B [MeSH Supplementary Concept]
- ptprn protein, rat [MeSH Supplementary Concept]
- tyrosine phosphatase inhibitor-3 [MeSH Supplementary Concept]
Record concept(s)
- protein tyrosine phosphatases [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACP1 protein, human [MeSH Supplementary Concept]
- Acp1 protein, mouse [MeSH Supplementary Concept]
- Acp1 protein, rat [MeSH Supplementary Concept]
- Argp protein, Drosophila [MeSH Supplementary Concept]
- At3g52180 protein, arabidopsis [MeSH Supplementary Concept]
- B59 protein, human [MeSH Supplementary Concept]
- CDC14 protein, S cerevisiae [MeSH Supplementary Concept]
- CDC14A protein, human [MeSH Supplementary Concept]
- CDC14A protein, mouse [MeSH Supplementary Concept]
- Cdkn3 protein, mouse [MeSH Supplementary Concept]
- Clp1 protein, S. pombe [MeSH Supplementary Concept]
- CpsB protein, streptococcus pneumoniae [MeSH Supplementary Concept]
- DDSP protein, human [MeSH Supplementary Concept]
- Dusp4 protein, mouse [MeSH Supplementary Concept]
- EAK-4 protein, C elegans [MeSH Supplementary Concept]
- EAK-6 protein, C elegans [MeSH Supplementary Concept]
- EDTP protein, drosophila [MeSH Supplementary Concept]
- EGG-3 protein, C elegans [MeSH Supplementary Concept]
- EYA protein, arabidopsis [MeSH Supplementary Concept]
- EYA1 protein, human [MeSH Supplementary Concept]
- EYA2 protein, human [MeSH Supplementary Concept]
- EYA3 protein, human [MeSH Supplementary Concept]
- Eya1 protein, mouse [MeSH Supplementary Concept]
- Eya1 protein, xenopus [MeSH Supplementary Concept]
- Eya2 protein, mouse [MeSH Supplementary Concept]
- HACD1 protein, human [MeSH Supplementary Concept]
- HACD2 protein, human [MeSH Supplementary Concept]
- Hacd1 protein, mouse [MeSH Supplementary Concept]
- Hacd1 protein, rat [MeSH Supplementary Concept]
- HmLAR1 protein, hirudo medicinalis [MeSH Supplementary Concept]
- HmLAR2 protein, hirudo medicinalis [MeSH Supplementary Concept]
- IDA-1 protein, C elegans [MeSH Supplementary Concept]
- Kek1 protein, drosophila [MeSH Supplementary Concept]
- LTP1 protein, S cerevisiae [MeSH Supplementary Concept]
- MKP1 protein, arabidopsis [MeSH Supplementary Concept]
- MKP2 protein, arabidopsis [MeSH Supplementary Concept]
- MSG5 protein, S cerevisiae [MeSH Supplementary Concept]
- MptpA protein, mycobacterium tuberculosis [MeSH Supplementary Concept]
- PHS1 protein, arabidopsis [MeSH Supplementary Concept]
- PPS1 protein, S cerevisiae [MeSH Supplementary Concept]
- PRL-1 protein, drosophila [MeSH Supplementary Concept]
- PRL-3 protein, rat [MeSH Supplementary Concept]
- PTP-3 protein, C elegans [MeSH Supplementary Concept]
- PTP-ER protein, drosophila [MeSH Supplementary Concept]
- PTP1 protein, Arabidopsis [MeSH Supplementary Concept]
- PTP4A1 protein, human [MeSH Supplementary Concept]
- PTP4A2 protein, human [MeSH Supplementary Concept]
- PTP4A3 protein, Xenopus [MeSH Supplementary Concept]
- PTP4A3 protein, human [MeSH Supplementary Concept]
- PTP99A protein, drosophila [MeSH Supplementary Concept]
- PTPIP51 protein, mouse [MeSH Supplementary Concept]
- PTPN13 protein, Xenopus [MeSH Supplementary Concept]
- PTPRT protein, rat [MeSH Supplementary Concept]
- PTPX1 protein, xenopus [MeSH Supplementary Concept]
- PTPX10 protein, xenopus [MeSH Supplementary Concept]
- Ptp10D protein, drosophila [MeSH Supplementary Concept]
- Ptp2 protein, S cerevisiae [MeSH Supplementary Concept]
- Ptp4a1 protein, mouse [MeSH Supplementary Concept]
- Ptp4a1 protein, rat [MeSH Supplementary Concept]
- Ptp4a2 protein, mouse [MeSH Supplementary Concept]
- Ptp4a3 protein, mouse [MeSH Supplementary Concept]
- Ptp52F protein, drosophila [MeSH Supplementary Concept]
- PtpA protein, Mycobacterium avium ssp. paratuberculosis [MeSH Supplementary Concept]
- PtpB protein, S cerevisiae [MeSH Supplementary Concept]
- Ptpcd-1 protein, mouse [MeSH Supplementary Concept]
- Ptpmt1 protein, human [MeSH Supplementary Concept]
- Ptpmt1 protein, mouse [MeSH Supplementary Concept]
- Ptpmt1 protein, rat [MeSH Supplementary Concept]
- RMDN3 protein, human [MeSH Supplementary Concept]
- Rmdn3 protein, rat [MeSH Supplementary Concept]
- SDF-9 protein, C elegans [MeSH Supplementary Concept]
- Siw14 protein, S cerevisiae [MeSH Supplementary Concept]
- Ssu72 protein, drosophila [MeSH Supplementary Concept]
- Stp1 protein, S pombe [MeSH Supplementary Concept]
- TULA-2 protein, mouse [MeSH Supplementary Concept]
- UBASH3B protein, human [MeSH Supplementary Concept]
- YGR203w protein, S cerevisiae [MeSH Supplementary Concept]
- eya-1 protein, C elegans [MeSH Supplementary Concept]
- eya1 protein, zebrafish [MeSH Supplementary Concept]
- eya3 protein, xenopus [MeSH Supplementary Concept]
- lip-1 protein, C elegans [MeSH Supplementary Concept]
- low-molecular-mass dual-specificity phosphatase-2 [MeSH Supplementary Concept]
- mop protein, drosophila [MeSH Supplementary Concept]
- mtm-9 protein, C elegans [MeSH Supplementary Concept]
- pez protein, drosophila [MeSH Supplementary Concept]
- phosphotyrosine phosphatase eta [MeSH Supplementary Concept]
- primo-1 protein, Drosophila [MeSH Supplementary Concept]
- prostatic acid phosphatase [MeSH Supplementary Concept]
- prostatic acid phosphatase (248-286), human [MeSH Supplementary Concept]
- protein-tyrosine phosphatase, nostoc [MeSH Supplementary Concept]
- ptp-1 protein, C elegans [MeSH Supplementary Concept]
- ptp4a3a protein, zebrafish [MeSH Supplementary Concept]
- ptpn21 protein, zebrafish [MeSH Supplementary Concept]
- pyp1 protein, S pombe [MeSH Supplementary Concept]
- pyp2 protein, S pombe [MeSH Supplementary Concept]
- pyp3 protein, S pombe [MeSH Supplementary Concept]
- sptP protein, salmonella typhimurium [MeSH Supplementary Concept]
- stg protein, drosophila [MeSH Supplementary Concept]
- striatal-enriched tyrosine phosphatase 61, mouse [MeSH Supplementary Concept]
- yop51 protein, yersinia enterocolitica [MeSH Supplementary Concept]
- yopH protein, yersinia [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Protein Tyrosine Phosphatase Gene [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protein Tyrosine Phosphatase [NCIt concept]
- Protein-tyrosine-phosphatase (substance) [SNOMED CT concept]
- protein-tyrosine-phosphatase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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