Non-Receptor Type Protein Tyrosine Phosphatase

Preferred Label : Non-Receptor Type Protein Tyrosine Phosphatase;

NCIt synonyms : Tyrosine-Protein Phosphatase Non-Receptor Type; Protein Tyrosine Phosphatase Non-Receptor Type; Non-Receptor Protein Tyrosine Phosphatase; Cytosolic Protein Tyrosine Phosphatase; Non-Receptor PTPase; PTPN;

NCIt definition : A group of cytosolic enzymes that specifically remove tyrosine-bound phosphate groups from many phosphoproteins, including many enzymes phosphorylated by a tyrosine kinase. These proteins play a role in the modulation of tyrosine phosphorylation and dephosphorylation in cellular signaling pathways.;

Détails

Origin ID

C106408;

UMLS CUI

C1955972;

Automatic exact mappings (from CISMeF team)
- protein tyrosine phosphatases, Non-Receptor [MeSH concept]
- protein tyrosine phosphatases, Non-Receptor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- protein tyrosine phosphatases, Non-Receptor [MeSH Descriptor]
- protein tyrosine phosphatases, Non-Receptor [MeSH concept]
concept_is_in_subset
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Non-Receptor Protein Tyrosine Phosphatase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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