Dual Specificity Protein Phosphatase 6

Preferred Label : Dual Specificity Protein Phosphatase 6;

NCIt synonyms : Dual Specificity Protein Phosphatase PYST1; Dual-Specificity Protein Phosphatase 6; MKP-3; EC 3.1.3.48; EC 3.1.3.16; Mitogen-Activated Protein Kinase Phosphatase 3; MAP Kinase Phosphatase 3; DUSP6;

NCIt definition : Dual specificity protein phosphatase 6 (381 aa, 42 kDa) is encoded by the human DUSP6 gene. This protein plays a role in both dephosphorylation and inactivation of mitogen-activated protein kinases.;

Details

Origin ID

C106026;

UMLS CUI

C1608529;

Automatic exact mappings (from CISMeF team)
- Dual-specificity phosphatase 6 [OMIM gene]
- dual specificity phosphatase 6 [MeSH Descriptor]
- dual specificity phosphatase 6 [ORDO Gene]
OMIM relation
- Dual-specificity phosphatase 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DUSP6 protein, human [MeSH Supplementary Concept]
- DUSP6 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DUSP6 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- MAP Kinase Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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