Tyrosine-Protein Phosphatase Non-Receptor Type 2

Preferred Label : Tyrosine-Protein Phosphatase Non-Receptor Type 2;

NCIt synonyms : EC 3.1.3.48; T-Cell Protein Tyrosine Phosphatase; TCPTP; T-Cell Protein-Tyrosine Phosphatase; PTPN2;

NCIt definition : Tyrosine-protein phosphatase non-receptor type 2 (415 aa, 48 kDa) is encoded by the human PTPN2 gene. This protein is involved in the removal of phosphate groups from receptor tyrosine kinase proteins.;

Détails

Origin ID

C138103;

UMLS CUI

C1869329;

Automatic exact mappings (from CISMeF team)
- Protein-tyrosine phosphatase, nonreceptor-type, 2 [OMIM gene]
- protein tyrosine phosphatase non-receptor type 2 [ORDO Gene]
- protein tyrosine phosphatase, Non-Receptor type 2 [MeSH Descriptor]
- protein tyrosine phosphatase, Non-Receptor type 2 [MeSH concept]
OMIM relation
- Protein-tyrosine phosphatase, nonreceptor-type, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PTPN2 protein, human [MeSH Supplementary Concept]
- PTPN2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Non-Receptor Protein Tyrosine Phosphatase Gene [NCIt concept]
- PTPN2 Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth Regulation [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Osunprotafib [NCIt concept]
- PTPN2/1 Inhibitor ABBV-CLS-579 [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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