Preferred Label : protein tyrosine phosphatase, Non-Receptor type 2;
MeSH definition : A subtype of non-receptor protein tyrosine phosphatase that is closely-related to
PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA
for this phosphatase results in the production at two gene products, one of which
includes a C-terminal nuclear localization domain that may be involved in the transport
of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein
tyrosine phosphatase the expression of this subtype occurs widely.;
MeSH synonym : tcptp enzyme; T-Cell Protein Tyrosine Phosphatase; t cell protein tyrosine phosphatase; tc-ptp; protein tyrosine phosphatase, non receptor type 2;
MeSH hyponym : protein tyrosine phosphatase, Non-Receptor type 2, TC45 isoform; protein tyrosine phosphatase, Non-Receptor type 2, TC48 isoform; TC48 Protein Tyrosine Phosphatase; TC48 Enzyme; TC45 Protein Tyrosine Phosphatase; TC45 Enzyme;
MeSH Related Number : protein tyrosine phosphatase, Non-Receptor type 2, TC48 isoform; protein tyrosine phosphatase, Non-Receptor type 2, TC45 isoform; EC 3.1.3.48;
Registry Number MeSH : EC 3.1.3.48;
Related CAS MeSH : EC 3.1.3.48 (Protein tyrosine phosphatase, Non-Receptor type 2, TC48 isoform); EC 3.1.3.48 (Protein tyrosine phosphatase, Non-Receptor type 2, TC45 isoform);
Is substance : O;
UNII : EC 3.1.3.48;
Origin ID : D054578;
UMLS CUI : C0252270;
Allowable qualifiers
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A subtype of non-receptor protein tyrosine phosphatase that is closely-related to
PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA
for this phosphatase results in the production at two gene products, one of which
includes a C-terminal nuclear localization domain that may be involved in the transport
of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein
tyrosine phosphatase the expression of this subtype occurs widely.
