Non-Receptor Protein Tyrosine Phosphatase Gene - CISMeF
Non-Receptor Protein Tyrosine Phosphatase GeneNCIt concept
Preferred Label : Non-Receptor Protein Tyrosine Phosphatase Gene;
NCIt synonyms : Cytosolic Protein Tyrosine Phosphatase Gene; Non-Receptor Type Protein Tyrosine Phosphatase Gene;
NCIt definition : Non-Receptor Protein Tyrosine Phosphatase Genes encode Non-Receptor Protein Tyrosine
Phosphatases, one of the two main categories (soluble and transmembrane receptor)
of enzymes that catalyze removal of a tyrosine-attached phosphate group and are important
in control of cell growth, proliferation, differentiation, and transformation. Two
cysteines in the catalytic domain (one absolutely required for activity) are generally
conserved; other conserved residues in the vicinity are important. (NCI);