Non-Receptor Protein Tyrosine Phosphatase Gene

Preferred Label : Non-Receptor Protein Tyrosine Phosphatase Gene;

NCIt synonyms : Cytosolic Protein Tyrosine Phosphatase Gene; Non-Receptor Type Protein Tyrosine Phosphatase Gene; PTPN Family Gene;

NCIt definition : Non-Receptor Protein Tyrosine Phosphatase Genes encode Non-Receptor Protein Tyrosine Phosphatases, one of the two main categories (soluble and transmembrane receptor) of enzymes that catalyze removal of a tyrosine-attached phosphate group and are important in control of cell growth, proliferation, differentiation, and transformation. Two cysteines in the catalytic domain (one absolutely required for activity) are generally conserved; other conserved residues in the vicinity are important. (NCI);

Détails

Origin ID

C25972;

UMLS CUI

C1335055;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Non-Receptor Type Protein Tyrosine Phosphatase [NCIt concept]
- Protein Tyrosine Phosphatase Type IVA 1 [NCIt concept]
- Protein Tyrosine Phosphatase Type IVA 3 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 1 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 11 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 12 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 13 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 14 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 2 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 21 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 22 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 6 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 7 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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