Dual Specificity Protein Phosphatase 1

Preferred Label : Dual Specificity Protein Phosphatase 1;

NCIt synonyms : MAP Kinase Phosphatase-1; Dual-Specificity Phosphatase 1; MAP Kinase Phosphatase 1; Protein-Tyrosine Phosphatase, Nonreceptor-Type, 10; Dual Specificity Protein Phosphatase hVH1; DUSP1; MKP-1; Protein-Tyrosine Phosphatase CL100; EC 3.1.3.16; Serine/Threonine Specific Protein Phosphatase; EC 3.1.3.48; Dual Specificity Phosphatase-1; Dual Specificity Phosphatase 1; Mitogen-Activated Protein Kinase Phosphatase 1;

NCIt definition : Dual specificity protein phosphatase 1 (367 aa, 39 kDa) is encoded by the human DUSP1 gene. This protein plays a role in the dephosphorylation of mitogen-activated protein kinase 1.;

Details

Origin ID

C29568;

UMLS CUI

C0287531;

OMIM relation
- Dual-specificity phosphatase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DUSP1 protein, human [MeSH concept]
- DUSP1 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- DUSP1 protein, human [MeSH concept]
- DUSP1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- DUSP1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- MAP Kinase Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Regulation of p38-alpha and p38-beta Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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