Receptor-Type Tyrosine-Protein Phosphatase C

Preferred Label : Receptor-Type Tyrosine-Protein Phosphatase C;

NCIt synonyms : PTPRC; T200 Glycoprotein; CD45RABC; Leukocyte Common Antigen; CD45 Antigen; EC 3.1.3.48; L-CA; T200; Protein Tyrosine Phosphatase Receptor Type-C; Receptor-Type Tyrosine-Protein Phosphatase C Isoform 1;

NCIt related terms : CD45;

NCIt definition : Receptor-type tyrosine-protein phosphatase C (1304 aa, 147 kDa) is encoded by the human PTPRC gene. This protein plays a role in protein dephosphorylation.;

Details

Origin ID

C17282;

UMLS CUI

C1870006;

Currated CISMeF NLP mapping
- Leukocyte Common Antigens [MeSH Descriptor]
- Leukocyte Common Antigens [MeSH concept]
False automatic mappings
- Left main coronary artery [ICD-11 Extension code]
OMIM relation
- Protein-tyrosine phosphatase, receptor-type, C [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PTPRC protein, human [MeSH concept]
- PTPRC protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- EWS Authorized Value Terminology [NCIt concept]
- EWS Immunohistochemistry Table [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PTPRC Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Lymphocyte Cell Surface Molecule Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Cytotoxic T Cell Surface Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T Helper Cell Surface Molecule Pathway [NCIt concept]
- TCR Activation Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Multiple Sclerosis [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
is_target
- Anti-CD45 Monoclonal Antibody [NCIt concept]
- Anti-CD45 Monoclonal Antibody AHN-12 [NCIt concept]
- Astatine At 211 Anti-CD45 Monoclonal Antibody BC8-B10 [NCIt concept]
- Indium In 111 Anti-CD45 Monoclonal Antibody BC8 [NCIt concept]
- Iodine I 131 Apamistamab [NCIt concept]
- Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12 [NCIt concept]
- Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8 [NCIt concept]

Keyword's position in hierarchy(ies) :

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