Preferred Label : Yttrium Y 90 Anti-CD45 Monoclonal Antibody AHN-12;
NCIt synonyms : Y 90 AHN-12;
NCIt definition : A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the
radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y
90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on
the surface of normal and malignant hematopoietic cells. After binding and internalization
by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.;
NCI Metathesaurus CUI : CL383503;
Origin ID : C74093;
UMLS CUI : C2349172;
Semantic type(s)
- concept_is_in_subset
- has_target
