PTPRC Gene - CISMeF

Preferred Label : PTPRC Gene;

NCIt synonyms : Protein Tyrosine Phosphatase, Receptor Type C Gene; CD45;

NCIt related terms : PTPRC;

CISMeF acronym : PTPRC;

NCIt definition : This gene plays a role in suppression of cytokine receptor signaling and the regulation of signal transduction in lymphocytes.;

Details

Origin ID

C24711;

UMLS CUI

C1335285;

Automatic exact mappings (from CISMeF team)
- CD45 [LOINC component]
- CD45 Ag [LOINC component]
- Leukocyte Common Antigens [MeSH Descriptor]
- Leukocyte common Ag [LOINC component]
- Protein-tyrosine phosphatase, receptor-type, C [OMIM gene]
- protein tyrosine phosphatase receptor type C [ORDO Gene]
HGNC gene
- protein tyrosine phosphatase receptor type C [HGNC gene]
OMIM relation
- Protein-tyrosine phosphatase, receptor-type, C [OMIM gene]
See also inter- (CISMeF)
- CD45 (Lymphs) cells [LOINC component]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Protein-tyrosine phosphatase, receptor-type, C [OMIM gene]
- protein tyrosine phosphatase receptor type C [HGNC gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Reference Gene Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_associated_with_disease
- Multiple Sclerosis [NCIt concept]
gene_encodes_gene_product
- CD45RA [NCIt concept]
- CD45RB [NCIt concept]
- CD45RC [NCIt concept]
- CD45RO [NCIt concept]
- PTPRC Gene Product [NCIt concept]
- Receptor-Type Tyrosine-Protein Phosphatase C [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_mapped_to_disease
- IL-7R-Alpha-deficient Severe Combined Immunodeficiency [NCIt concept]
- Severe Combined Immunodeficiency due to CD45 Deficiency [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
genetic_biomarker_related_to
- Anti-CD45RA Antibody [NCIt concept]
- B220 Staining Method [NCIt concept]
- CD45 to Lymphocyte Ratio Measurement [NCIt concept]
- CD45-Positive Neoplastic Cells Present [NCIt concept]
- CD45RA to Lymphocyte Ratio Measurement [NCIt concept]
- CD45RO Antibody [NCIt concept]
- Neoplastic Cells with CD45 Dim-to-Negative Expression Present [NCIt concept]
- PTPRC Antibody [NCIt concept]
- PTPRC Negative [NCIt concept]
- PTPRC Positive [NCIt concept]
- Severe Combined Immunodeficiency due to CD45 Deficiency [NCIt concept]

Keyword's position in hierarchy(ies) :

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