Preferred Label : Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8;
NCIt synonyms : 90Y Anti-CD45 MoAb BC8;
NCIt definition : A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb)
BC8 labeled with yttrium 90 (Y90), with potential immunotherapeutic activity. Yttrium
Y 90 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein-tyrosine
phosphatase expressed on the surface of both normal and malignant hematopoietic cells.
After binding and internalization by CD45-expressing tumor cells, this agent may deliver
a cytotoxic dose of beta radiation.;
NCI Metathesaurus CUI : CL428164;
Origin ID : C95698;
UMLS CUI : C2987339;
Semantic type(s)
- concept_is_in_subset
- has_target
