CD45RA - CISMeF

Preferred Label : CD45RA;

NCIt synonyms : Receptor-Type Tyrosine-Protein Phosphatase C Isoform CD45RA; CD45RA Antigen; Receptor-Type Tyrosine-Protein Phosphatase C Isoform 6;

NCIt definition : CD45RA (1211 aa, 138 kDa) is encoded by the human PTPRC gene. This protein plays a role in both lymphocyte function and protein dephosphorylation. It is an isoform of receptor-type tyrosine-protein phosphatase C that is missing the amino acids encoded by exons 5 and 6 of the PTPRC gene.;

Details

Origin ID

C118492;

UMLS CUI

C5441599;

Automatic exact mappings (from CISMeF team)
- CD45RA antigens [MeSH concept]
- Leukocyte Common Antigens [MeSH Descriptor]
OMIM relation
- Protein-tyrosine phosphatase, receptor-type, C [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD45RA [LOINC component]
- CD45RA antigens [MeSH concept]
- Lymphocyte antigen CD45RA (substance) [SNOMED CT concept]
- lymphocyte antigen cd45ra [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PTPRC Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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