Dual Specificity Protein Phosphatase 4

Preferred Label : Dual Specificity Protein Phosphatase 4;

NCIt synonyms : VH1 Homologous Phosphatase 2; EC 3.1.3.16; MAP Kinase Phosphatase 2; DUSP4; Dual-Specificity Phosphatase 4; Dual-Specificity Protein Phosphatase 4; Dual Specificity Protein Phosphatase HVH2; MKP-2; EC 3.1.3.48; Mitogen-Activated Protein Kinase Phosphatase 2; VH1-Like Phosphatase 2;

NCIt definition : Dual specificity protein phosphatase 4 (394 aa, 43 kDa) is encoded by the human DUSP4 gene. This protein is involved in the dephosphorylation of mitogen-activated protein kinase-1 and -3.;

Details

Origin ID

C112129;

UMLS CUI

C0298690;

Automatic exact mappings (from CISMeF team)
- Dual-specificity phosphatase 4 [OMIM gene]
- dual specificity phosphatase 4 [HGNC gene]
OMIM relation
- Dual-specificity phosphatase 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DUSP4 protein, human [MeSH Supplementary Concept]
- DUSP4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DUSP4 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- MAPK Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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