Tyrosine-Protein Phosphatase Non-Receptor Type 12

Preferred Label : Tyrosine-Protein Phosphatase Non-Receptor Type 12;

NCIt synonyms : PTPN12; Protein Tyrosine Phosphatase G1; Protein Tyrosine Phosphatase, Non-Receptor Type 12; PTPG1; EC 3.1.3.48; PTP-PEST; Non-Receptor Type 12 Protein Tyrosine Phosphatase;

NCIt definition : Tyrosine-protein phosphatase non-receptor type 12 (780 aa, 88 kDa) is encoded by the human PTPN12 gene. This protein plays a role in both cytoskeleton morphology and protein dephosphorylation.;

Details

Origin ID

C26341;

UMLS CUI

C1869547;

Currated CISMeF NLP mapping
- protein tyrosine phosphatase, Non-Receptor type 12 [MeSH Descriptor]
- protein tyrosine phosphatase, Non-Receptor type 12 [MeSH concept]
OMIM relation
- Protein-tyrosine phosphatase, nonreceptor-type, 12 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PTPN12 protein, human [MeSH concept]
- PTPN12 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Non-Receptor Protein Tyrosine Phosphatase Gene [NCIt concept]
- PTPN12 Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Tyrosine Phosphatase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- PTB Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Colon Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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