Methylcrotonoyl-CoA Carboxylase Beta Chain, Mitochondrial

Preferred Label : Methylcrotonoyl-CoA Carboxylase Beta Chain, Mitochondrial;

NCIt synonyms : Methylcrotonoyl-CoA Carboxylase Beta; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin Containing Subunit; Methylcrotonoyl-CoA Carboxylase 2; MCCC2; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin-Containing Subunit; 3-Methylcrotonyl-CoA:Carbon Dioxide Ligase Subunit Beta; 3-Methylcrotonyl-CoA Carboxylase 2; EC 6.4.1.4; MCCase Subunit Beta; Testicular Secretory Protein Li 29;

NCIt definition : Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (563 aa, 61 kDa) is encoded by the human MCCC2 gene. This protein is involved in catalyzing the carboxylation of 3-methylcrotonyl-CoA to yield 3-methylglutaconyl-CoA.;

NCIt note : 3-methylcrotonyl-CoA carboxylase (MCCC) is likely a dodecamer composed of six biotin-containing alpha subunits (MCCC1) and six beta (MCCC2) subunits.;

Details

Origin ID

C190388;

UMLS CUI

C4276583;

Automatic exact mappings (from CISMeF team)
- 3-methylcrotonyl-coa carboxylase 2 [OMIM gene]
- methylcrotonyl-CoA carboxylase subunit 2 [HGNC gene]
- methylcrotonyl-CoA carboxylase subunit 2 [ORDO Gene]
OMIM relation
- 3-methylcrotonyl-coa carboxylase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- methylcrotonoyl-CoA carboxylase 2, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- MCCC2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Valine, Leucine and Isoleucine Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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