" /> E3 SUMO-Protein Ligase CBX4 - CISMeF





Preferred Label : E3 SUMO-Protein Ligase CBX4;

NCIt synonyms : Pc2; hPc2; Polycomb 2 Homolog; Chromobox Protein Homolog 4; CBX4; EC 2.3.2.-;

NCIt definition : E3 SUMO-protein ligase CBX4 (558 aa, 61 kDa) is encoded by the human CBX4 gene. This soluble, nuclear protein plays a role in repressing the expression of genes through SUMOylation of lysine 119 of histone H2A.;

NCIt note : Functions together with UBE2I ubiquitin conjugating enzyme, which together with CBX4, are components of the PRC1 complex. UBE2I is essential for nuclear architecture and chromosome segregation.;

Détails


Vous pouvez consulter :


Nous contacter.
29/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.