Endoribonuclease Dicer

Preferred Label : Endoribonuclease Dicer;

NCIt synonyms : Helicase-MOI; Dicer; K12H4.8-Like; Helicase with RNase Motif; DICER1 Protein; Double-Stranded RNA-Specific Endoribonuclease; KIAA0928; Homolog of Drosophila Dicer; Dcr-1 Homolog; HERNA; DICER1; Helicase MOI; EC 3.1.26.3; Dicer 1, Double-Stranded RNA-Specific Endoribonuclease;

NCIt definition : Endoribonuclease Dicer (1922 aa, 219 kDa) is encoded by the human DICER1 gene. This protein plays a role in both pri-miRNA processing and RNA interference.;

Details

Origin ID

C25961;

UMLS CUI

C1309483;

OMIM relation
- Dicer 1, ribonuclease III [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DICER1 protein, human [MeSH Supplementary Concept]
- DICER1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DICER1 Gene [NCIt concept]
- Endoribonuclease Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ribonuclease Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- RNA Helicase [NCIt concept]
gene_product_has_chemical_classification
- RNase III Family Protein [NCIt concept]
gene_product_has_gene_product_variant
- DICER1 NP_803187.1:p.D1810H [NCIt concept]
- DICER1 NP_803187.1:p.E1705V [NCIt concept]
- DICER1 NP_803187.1:p.E1813D [NCIt concept]
- DICER1 NP_803187.1:p.E1813G [NCIt concept]
- DICER1 NP_803187.1:p.E1813K [NCIt concept]
- DICER1 NP_803187.1:p.W1831* [NCIt concept]
- DICER1 NP_803187.1:p.W1831X [NCIt concept]
- DICER1 NP_803187.1:p.Y1225X [NCIt concept]
- DICER1 Protein Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Double-Stranded RNA Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Dicer Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Gene Regulation Process [NCIt concept]
- Hydrolysis [NCIt concept]
- MicroRNA Synthesis [NCIt concept]
- RNA Interference [NCIt concept]

Keyword's position in hierarchy(ies) :

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