Immunity-Related GTPase Family M Protein

Preferred Label : Immunity-Related GTPase Family M Protein;

NCIt synonyms : LPS-Stimulated RAW 264.7 Macrophage Protein 47 Homolog; LRG-47; EC 3.6.5.-; Immunity-Related GTPase Family M Protein 1; Interferon-Inducible Protein 1; IRGM;

NCIt definition : Immunity-related GTPase family M protein (181 aa, 20 kDa) is encoded by the human IRGM gene. This protein is involved in the mediation of GTP hydrolysis that is involved in the regulation of innate immunity.;

Details

Origin ID

C97239;

UMLS CUI

C3273299;

OMIM relation
- Immunity-related gtpase family, M [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- IRGM Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Autophagosome [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Hydrolysis [NCIt concept]
- Immune System Process [NCIt concept]
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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