Cytochrome P450 11B2, Mitochondrial

Preferred Label : Cytochrome P450 11B2, Mitochondrial;

NCIt synonyms : Aldosterone Synthase; P-450C18; Cytochrome P450 Subfamily XIB (Steroid 11-Beta-Hydroxylase) Polypeptide 2; Steroid 18-Hydroxylase; Aldosterone-Synthesizing Enzyme; Steroid 11-Beta-Monooxygenase; Steroid 11-Beta/18-Hydroxylase; Mitochondrial Cytochrome P450 11B2; CYPXIB2; P-450Aldo; Cytochrome P450 Subfamily XIB Polypeptide 2; ALDOS; Cytochrome P-450Aldo; EC 1.14.15.4; EC 1.14.15.5; Cytochrome P-450C18; Cytochrome-P450-11B2; CYP11B2; Cytochrome P450 11B2;

NCIt definition : Cytochrome P450 11B2, mitochondrial (503 aa, 58 kDa) is encoded by the human CYP11B2 gene. This protein plays a role in corticosterone metabolism.;

Details

Origin ID

C40064;

UMLS CUI

C1527416;

OMIM relation
- Cytochrome p450, subfamily xib, polypeptide 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
Validated automatic mappings to NTBT
- Cytochrome P-450 CYP11B2 [MeSH Descriptor]
- Cytochrome P-450 CYP11B2 [MeSH concept]
gene_encodes_gene_product
- CYP11B2 Gene [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Hydroxylation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
is_target
- CYP17/CYP11B2 Inhibitor LAE001 [NCIt concept]
- Osilodrostat [NCIt concept]

Keyword's position in hierarchy(ies) :

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