Serum Paraoxonase/Arylesterase 1

Preferred Label : Serum Paraoxonase/Arylesterase 1;

NCIt synonyms : Aromatic Esterase 1; EC 3.1.1.2; Serum Aryldialkylphosphatase 1; PON 1; EC 3.1.8.1; K-45; EC 3.1.1.81; Paraoxonase B-Type; A-Esterase 1; Serum Aryldiakylphosphatase; Arylesterase B-Type; Esterase A; PON1;

NCIt definition : Serum paraoxonase/arylesterase 1 (355 aa, 40 kDa) is encoded by the human PON1 gene. This protein plays a role in the catabolism of aromatic carboxylic acid esters, organophosphates and lactones.;

NCI Metathesaurus CUI : CL473691;

Details

Origin ID

C116049;

UMLS CUI

C1257646;

Automatic exact mappings (from CISMeF team)
- Aryldialkylphosphatase (substance) [SNOMED CT concept]
- Arylesterase (substance) [SNOMED CT concept]
- Ces1c protein, mouse [MeSH Supplementary Concept]
- Esterase (substance) [SNOMED CT concept]
- Paraoxonase 1 [OMIM Phenotype]
- carboxylesterase activity [GO term]
- carboxylic ester hydrolase activity [GO term]
- esterases [MeSH concept]
- esterases [MeSH Descriptor]
- paraoxonase 1 [ORDO Gene]
- paraoxonase 1 [HGNC gene]
OMIM relation
- Paraoxonase 1 [OMIM Phenotype]
See also inter- (CISMeF)
- Esterase [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PON1 protein, human [MeSH Supplementary Concept]
- PON1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PON1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Aryldialkylphosphatase [NCIt concept]
- Arylesterase [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Detoxification [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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