Deubiquitinase MYSM1

Preferred Label : Deubiquitinase MYSM1;

NCIt synonyms : 2A-DUB; EC 3.4.19.-; Myb-Like, SWIRM and MPN Domains-Containing Protein 1; MYSM1; Myb-Like, SWIRM and MPN Domain-Containing Protein 1; Histone H2A Deubiquitinase MYSM1;

NCIt definition : Deubiquitinase MYSM1 (828 aa, 95 kDa) is encoded by the human MYSM1 gene. This protein is involved in the deubiquitination of histone 2A, which leads to chromatin remodeling and transcriptional activation.;

Details

Origin ID

C113235;

UMLS CUI

C1958029;

Automatic exact mappings (from CISMeF team)
- Myb like, SWIRM and MPN domains 1 [ORDO Gene]
- Myb-like, swirm, and mpn domains-containing protein 1 [OMIM gene]
OMIM relation
- Myb-like, swirm, and mpn domains-containing protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MYSM1 protein, human [MeSH Supplementary Concept]
- MYSM1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MYSM1 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
- Deubiquitinating Enzyme [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- SANT Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Deubiquitination [NCIt concept]
- Histone Modification [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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