ATP-Dependent RNA Helicase DHX58

Preferred Label : ATP-Dependent RNA Helicase DHX58;

NCIt synonyms : Probable ATP-Dependent Helicase LGP2; EC 3.6.4.13; DHX58; RIG-I-Like Receptor 3; RLR; RNA Helicase LGP2; RIG-I-Like Receptor LGP2; RLR-3; Protein D11Lgp2 Homolog; DEXH Box Polypeptide 58; Probable ATP-Dependent RNA Helicase DHX58;

NCIt definition : Probable ATP-dependent RNA helicase DHX58 (678 aa, 77 kDa) is encoded by the human DHX58 gene. This protein is involved in RNA binding and antiviral responses.;

NCI Metathesaurus CUI : CL937870;

Details

Origin ID

C158448;

UMLS CUI

C1957844;

Automatic exact mappings (from CISMeF team)
- DExH-box helicase 58 [HGNC gene]
- Dexh-box helicase 58 [OMIM gene]
OMIM relation
- Dexh-box helicase 58 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DHX58 protein, human [MeSH Supplementary Concept]
- DHX58 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- DHX58 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Immunity [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- RNA Processing [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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