" /> Heparanase - CISMeF





Preferred Label : Heparanase;

NCIt synonyms : Heparanase-1; HPSE; HPSE Protein; EC 3.2.1.166; Endo-Glucoronidase; Hpa1;

NCIt definition : Heparanase (543 aa, 61 kDa) is encoded by the human HPSE gene. This protein plays a role in proteoglycan catabolism.;

NCIt note : Heparan sulfate degradation is key in tumor cell and migrating leukocyte extravasation. Heparanase activity is also important in angiogenesis, wound healing, and smooth muscle proliferation.;

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31/07/2025


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