Protein Serine/Threonine Phosphatase

Preferred Label : Protein Serine/Threonine Phosphatase;

NCIt synonyms : Protein Serine-Threonine Phosphatase;

NCIt definition : Encoded by Protein Serine/Threonine Phosphatase Genes, Protein Serine/Threonine Phosphatases are a group of enzymes that specifically dephosphorylate phosphoserine and phosphothreonine residues in specific target proteins. Together with serine/threonine protein kinases, these enzymes regulate serine and threonine phosphorylation and dephosphorylation of target proteins in cellular signal transduction pathways typically involved in cell growth control.;

Details

Origin ID

C34078;

UMLS CUI

C0084210;

Automatic exact mappings (from CISMeF team)
- phosphoprotein phosphatases [MeSH Descriptor]
- phosphoprotein phosphatases [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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