Xylosyl- and Glucuronyltransferase LARGE1

Preferred Label : Xylosyl- and Glucuronyltransferase LARGE1;

NCIt synonyms : Glycosyltransferase-Like Protein LARGE1; EC 2.4.-.-; Acetylglucosaminyltransferase-Like 1A; LARGE1; Acetylglucosaminyltransferase-Like Protein; LARGE Xylosyl- and Glucuronyltransferase 1; Glycosyltransferase-Like Protein;

NCIt definition : Xylosyl- and glucuronyltransferase LARGE1 (756 aa, 88 kDa) is encoded by the human LARGE1 gene. This protein plays a role in both alpha-1,3-xylosyltransferase and beta-1,3-glucuronyltransferase activity.;

NCIt note : Xylosyl- and glucuronyltransferase LARGE1 is a bifunctional enzyme with activities that correspond to EC 2.4.1.- and EC 2.4.2.-. (UniProt);

Details

Origin ID

C202868;

UMLS CUI

C0764233;

OMIM relation
- Acetylglucosaminyltransferase-like protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LARGE1 protein, human [MeSH Supplementary Concept]
- LARGE1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- LARGE1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- O-Mannosyl Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- Glycosylation [NCIt concept]
- Histogenic Process [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients