Cytochrome B-245 Heavy Chain

Preferred Label : Cytochrome B-245 Heavy Chain;

NCIt synonyms : CYBB; CGD91-Phox; EC 1.6.3; Superoxide-Generating NADPH Oxidase Heavy Chain Subunit; Cytochrome B(558) Subunit Beta; Cytochrome B558 Subunit Beta; Heme-Binding Membrane Glycoprotein Gp91phox; Neutrophil Cytochrome B 91 kDa Polypeptide; NADPH Oxidase 2; p22 Phagocyte B-Cytochrome; gp91-1; gp91-phox; gp91 phox;

NCIt definition : Cytochrome B-245 heavy chain (570 aa, 65 kDa) is encoded by the human CYBB gene. This protein plays a role in the microbicidal activity of phagocytes.;

Details

Origin ID

C106596;

UMLS CUI

C1429424;

Automatic exact mappings (from CISMeF team)
- Cytochrome b(-245), beta subunit [OMIM gene]
- NADPH Oxidase 2 [MeSH Descriptor]
- NADPH Oxidase 2 [MeSH concept]
- cytochrome b-245 beta chain [ORDO Gene]
- cytochrome b-245 beta chain [HGNC gene]
OMIM relation
- Cytochrome b(-245), beta subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CYBB protein, human [MeSH Supplementary Concept]
- CYBB protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CYBB Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
gene_product_is_physical_part_of
- NADPH Oxidase Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Degranulation [NCIt concept]
- Ion Transport Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Oxidative Burst [NCIt concept]
- pH Homeostasis [NCIt concept]

Keyword's position in hierarchy(ies) :

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