Sphingomyelin Phosphodiesterase

Preferred Label : Sphingomyelin Phosphodiesterase;

NCIt synonyms : aSMase; Acid Sphingomyelinase; SMPD1; EC 3.1.4.12; Sphingomyelinase, Acid;

NCIt definition : Sphingomyelin phosphodiesterase (629 aa, 70 kDa) is encoded by the human SMPD1 gene. This protein plays a role in sphingomyelin catabolism.;

NCI Metathesaurus CUI : CL340955;

Details

Origin ID

C105021;

UMLS CUI

C2742829;

Automatic exact mappings (from CISMeF team)
- Acid sphingomyelinase [LOINC component]
- Acid sphingomyelinase (substance) [SNOMED CT concept]
- Sphingomyelin phosphodiesterase (substance) [SNOMED CT concept]
- Sphingomyelin phosphodiesterase 1, acid lysosomal [OMIM gene]
- Sphingomyelinase [OBSOLETE LOINC component]
- acid sphingomyelin phosphodiesterase activity [GO term]
- sphingomyelin phosphodiesterase [MeSH Descriptor]
- sphingomyelin phosphodiesterase [MeSH concept]
- sphingomyelin phosphodiesterase [SNOMED Notion]
- sphingomyelin phosphodiesterase 1 [ORDO Gene]
- sphingomyelin phosphodiesterase 1 [HGNC gene]
- sphingomyelin phosphodiesterase d [SNOMED Notion]
OMIM relation
- Sphingomyelin phosphodiesterase 1, acid lysosomal [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- SMPD1 protein, human [MeSH Supplementary Concept]
- SMPD1 protein, human [MeSH concept]
- Sphingomyelin phosphodiesterase (substance) [SNOMED CT concept]
- sphingomyelin phosphodiesterase [MeSH Descriptor]
- sphingomyelin phosphodiesterase [SNOMED Notion]
- sphingomyelin phosphodiesterase [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- SMPD1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lumen of the Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
- Sphingolipid Metabolism Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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