sphingomyelin phosphodiesterase

Preferred Label : sphingomyelin phosphodiesterase;

MeSH definition : An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.;

MeSH synonym : sphingomyelinase c; sphingomyelin cleaving enzyme; sphingomyelinase; Sphingomyelin Cholinephosphohydrolase;

MeSH CAS label : sphingomyelin cholinephosphohydrolase;

Registry Number MeSH : EC 3.1.4.12;

MeSH annotation : /defic: consider also NIEMANN-PICK DISEASE;

Wikipedia link : https://en.wikipedia.org/wiki/Sphingomyelin cholinephosphohydrolase;

Is substance : O;

UNII : EC 3.1.4.12;

Details

Origin ID

D013108;

UMLS CUI

C0037903;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- RY221B-a [MeSH Supplementary Concept]
- altenusin [MeSH Supplementary Concept]
- fantofarone [MeSH Supplementary Concept]
- scyphostatin [MeSH Supplementary Concept]
- tricyclodecane-9-yl-xanthogenate [MeSH Supplementary Concept]
Record concept(s)
- sphingomyelin phosphodiesterase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ASM-3 protein, C elegans [MeSH Supplementary Concept]
- ASMase, mouse [MeSH Supplementary Concept]
- ENPP7 protein, human [MeSH Supplementary Concept]
- SMPD1 protein, human [MeSH Supplementary Concept]
- SMPD3 protein, human [MeSH Supplementary Concept]
- SMPDL3A protein, human [MeSH Supplementary Concept]
- SMPDL3A protein, mouse [MeSH Supplementary Concept]
- SMPDL3B protein, human [MeSH Supplementary Concept]
- Smpd3 protein, mouse [MeSH Supplementary Concept]
- Smpd3 protein, rat [MeSH Supplementary Concept]
- TK4 sphingomyelinase [MeSH Supplementary Concept]
- acid sphingomyelinase-1 [MeSH Supplementary Concept]
- acid sphingomyelinase-2 [MeSH Supplementary Concept]
- alkaline sphingomyelinase, mouse [MeSH Supplementary Concept]
- hlb protein, Staphylococcus aureus [MeSH Supplementary Concept]
- intestinal alkaline sphingomyelinase, rat [MeSH Supplementary Concept]
- neutral sphingomyelinase 3, human [MeSH Supplementary Concept]
- neutral sphingomyelinase-1, human [MeSH Supplementary Concept]
- olipudase alfa [MeSH Supplementary Concept]
- sphingomyelinase I, loxosceles laeta [MeSH Supplementary Concept]
See also
- niemann-pick diseases [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Sphingomyelin Phosphodiesterase [NCIt concept]
- Sphingomyelin phosphodiesterase (substance) [SNOMED CT concept]
- sphingomyelin phosphodiesterase [SNOMED Notion]

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