Preferred Label : Cytochrome P450 2C19;
NCIt synonyms : CYP2C19; CYPIIC17; P450-11A; Mephenytoin 4'-Hydroxylase; Xenobiotic Monooxygenase; Cytochrome-P450-2C19; Mephenytoin 4-Prime-Hydroxylase; Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 19; Microsomal Monooxygenase; CYPIIC19; P450-254C; Flavoprotein-Linked Monooxygenase; Cytochrome P450, Family 2, Subfamily C, Polypeptide 19; (S)- Limonene 6-Monooxygenase; EC 1.14.13.49; Cytochrome P450-11A; EC 1.14.13.-; (R)- Limonene 6-Monooxygenase; EC 1.14.13.48; (S)- Limonene 7-Monooxygenase; Cytochrome P450-254C; Mephenytoin 4-Hydroxylase; EC 1.14.13.80;
NCIt definition : Cytochrome P450 2C19 (490 aa, 56 kDa) is encoded by the human CYP2C19 gene. This
protein is involved in steroid, terpenoid and drug metabolism.;
NCIt note : Substrates for cytochrome P450 2C19 include of a number of therapeutic agents such
as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates,
diazepam, propranolol, citalopram and imipramine. (UniProt);
Origin ID : C25948;
UMLS CUI : C0960580;
Automatic exact mappings (from CISMeF team)
OMIM relation
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
concept_is_in_subset
enzyme_metabolizes_chemical_or_drug
gene_encodes_gene_product
gene_product_has_chemical_classification
gene_product_has_organism_source
gene_product_has_structural_domain_or_motif
gene_product_is_element_in_pathway
gene_product_plays_role_in_biological_process