NCIt definition : A substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor
activity. Lansoprazole prodrug is converted to an active sulfonamide derivative in
the acidic environment of the gastric parietal cell; the sulfonamide derivative binds
to the gastric proton pump H /K ATPase and forms a stable disulfide bond with the
sulfhydryl group near the potassium-binding site on the luminal side, resulting in
inactivation of the ATPase and a reduction in gastric acid secretion. This agent does
not have anticholinergic or histamine H2 -receptor antagonistic properties.;
UNII : 0K5C5T2QPG;
InChIKey : MJIHNNLFOKEZEW-UHFFFAOYSA-N;
CAS number : 103577-45-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 103577-45-3
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