" /> Lansoprazole - CISMeF





Preferred Label : Lansoprazole;

NCIt definition : A substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. Lansoprazole prodrug is converted to an active sulfonamide derivative in the acidic environment of the gastric parietal cell; the sulfonamide derivative binds to the gastric proton pump H /K ATPase and forms a stable disulfide bond with the sulfhydryl group near the potassium-binding site on the luminal side, resulting in inactivation of the ATPase and a reduction in gastric acid secretion. This agent does not have anticholinergic or histamine H2 -receptor antagonistic properties.;

UNII : 0K5C5T2QPG;

InChIKey : MJIHNNLFOKEZEW-UHFFFAOYSA-N;

CAS number : 103577-45-3;

Drug name : Prevacid;

Chemical formula : C16H14F3N3O2S;

ChEBI ID : CHEBI:6375;

Codes from synonyms : 295;

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29/05/2025


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