Chloramphenicol

Preferred Label : Chloramphenicol;

NCIt synonyms : [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide;

NCIt definition : A semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit. The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation. As a result bacterial protein synthesis is blocked and impede bacterial cell proliferation.;

UNII : 66974FR9Q1;

InChIKey : WIIZWVCIJKGZOK-RKDXNWHRSA-N;

CAS number : 56-75-7;

Chemical formula : C11H12Cl2N2O5;

NSC code : 3069;

ChEBI ID : CHEBI:17698;

Codes from synonyms : NSC0003069; 00420;

Details

Origin ID

C363;

UMLS CUI

C0008168;

False automatic mappings
- Chloramphenicol group [ICD-10 Sub-category (who)]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Antibiotic chloramphenicol (group) [ICD-11 Extension code]
- Chloramphenicol [ICD-11 Extension code]
- Chloramphenicol [LOINC component]
- Chloramphenicol (class of antibiotic, substance) (substance) [Inactive SNOMED CT concept]
- Chloramphenicol (substance) [SNOMED CT concept]
- Chloramphenicol group [Bloc CIM-11]
- Product containing chloramphenicol (medicinal product) [SNOMED CT concept]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [Substance BNPC]
- chloramphenicol [MeSH concept]
- chloramphenicol [MeSH Descriptor]
- chloramphenicol, nos [SNOMED Notion]
Validated automatic mappings to BTNT
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
- chloramphenicol [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

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