NCIt definition : Cytochrome P450 3A4 (503 aa, 57 kDa) is encoded by the human CYP3A4 gene. This protein
is involved in the oxidation of steroids, fatty acids and xenobiotics.;
NCIt note : Cytochrome P450 3A4 oxidizes etoposide and converts aflatoxin B1 to a genotoxic derivative.;