NCIt definition : A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits
fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation
of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic
activity. Mammalian cell demethylation is much less sensitive to fluconazole inhibition.;
Alternative definition : NCI-GLOSS: A drug that treats infections caused by fungi.;