NCIt related terms : Cortogen; Cortone; Cortone acetate;
NCIt definition : The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally
occurring cortisone hormone produced by the adrenal glands with anti-inflammatory
and immunomodulating properties. Cortisone acetate diffuses through the cell membrane
and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to
promotor regions of certain genes and initiates RNA transcription. This results in
an induction of synthesis of certain anti-inflammatory proteins while inhibiting the
synthesis of certain inflammatory mediators.;
UNII : 883WKN7W8X;
InChIKey : ITRJWOMZKQRYTA-RFZYENFJSA-N;
CAS number : 50-04-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 50-04-4
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G-SRS /a ;
Drug name : Cortogen; Cortone;
Chemical formula : C23H30O6;
NSC code : 49420;
Codes from synonyms : NSC0049420; NSC0009703; 01058;