Cortisone Acetate

Preferred Label : Cortisone Acetate;

NCIt synonyms : 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione; 6alpha,9Difluoro-11beta,17,21-trihydroxypregna-1,4- diene-3,20-dione 21-acetate 17- Butyrate;

NCIt related terms : Cortogen; Cortone; Cortone acetate;

NCIt definition : The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.;

UNII : 883WKN7W8X;

InChIKey : ITRJWOMZKQRYTA-RFZYENFJSA-N;

CAS number : 50-04-4;

Drug name : Cortogen; Cortone;

Chemical formula : C23H30O6;

NSC code : 49420;

Codes from synonyms : NSC0049420; NSC0009703; 01058;

Details

Origin ID

C1058;

UMLS CUI

C0056391;

CISMeF manual mappings
- Cortisone acetate (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Cortisone [ICD-11 Extension code]
- cortisone [MeSH Descriptor]
- cortisone 21-acetate [Substance BNPC]
- cortisone acetate [MeSH concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Cortisone [ICD-11 Extension code]
- Cortisone acetate (substance) [SNOMED CT concept]
- Cortisone acetate preparation (product) [Inactive SNOMED CT concept]
- cortisone [MeSH Descriptor]
- cortisone 21-acetate [Substance BNPC]
- cortisone acetate [MeSH concept]
- cortisone acetate preparation [SNOMED Notion]
Validated automatic mappings to NTBT
- Cortisone (substance) [SNOMED CT concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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