" /> Finasteride - CISMeF





Preferred Label : Finasteride;

NCIt synonyms : (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;

NCIt definition : A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation.;

Alternative definition : NCI-GLOSS: A drug used to reduce the amount of male hormone (testosterone) produced by the body.;

UNII : 57GNO57U7G;

InChIKey : DBEPLOCGEIEOCV-WSBQPABSSA-N;

CAS number : 98319-26-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 98319-26-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Proscar; Prostide; Pro-Cure; Finastid; Chibro-Proscar; Urprosan; Propecia; Propeshia;

Molecule name : MK 906;

Chemical formula : C23H36N2O2;

ChEBI ID : CHEBI:5062;

Codes from synonyms : 01171; CDR0000045336; 221;

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06/05/2024


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