" /> Acetaminophen - CISMeF





Preferred Label : Acetaminophen;

NCIt synonyms : N-(4-Hydroxyphenyl)acetamide; 4-Hydroxyacetanilide; APAP;

NCIt related terms : Paracetamol; Tylenol;

NCIt definition : A p-aminophenol derivative with analgesic and antipyretic activities. Although the exact mechanism through which acetaminophen exert its effects has yet to be fully determined, acetaminophen may inhibit the nitric oxide (NO) pathway mediated by a variety of neurotransmitter receptors including N-methyl-D-aspartate (NMDA) and substance P, resulting in elevation of the pain threshold. The antipyretic activity may result from inhibition of prostaglandin synthesis and release in the central nervous system (CNS) and prostaglandin-mediated effects on the heat-regulating center in the anterior hypothalamus.;

Alternative definition : NCI-GLOSS: A drug that reduces pain and fever (but not inflammation). It belongs to the family of drugs called analgesics.;

UNII : 362O9ITL9D;

InChIKey : RZVAJINKPMORJF-UHFFFAOYSA-N;

CAS number : 103-90-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 103-90-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Tylenol;

Chemical formula : C8H9NO2;

NSC code : 109028; 3991;

ChEBI ID : CHEBI:46195;

Codes from synonyms : NSC0003991; 00589; CDR0000045165; 8;

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11/05/2024


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