Indinavir Sulfate

Preferred Label : Indinavir Sulfate;

NCIt synonyms : Indinavir; D-erythro-Pentonamide, 2,3,5-trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-, monohydrate, (1(1S,2R),5(S))-, sulfate (1:1) (salt);

NCIt definition : A synthetic antiviral agent. Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced.;

UNII : 771H53976Q;

InChIKey : NUBQKPWHXMGDLP-BDEHJDMKSA-N;

CAS number : 157810-81-6;

Drug name : Crixivan;

Molecule name : MK-639; DRG-0233; L-735,524;

Chemical formula : C36H47N5O4.H2SO4;

NSC code : 697197;

ChEBI ID : CHEBI:5899;

Details

Origin ID

C1662;

UMLS CUI

C0700483;

Automatic exact mappings (from CISMeF team)
- Indinavir [LOINC component]
- Indinavir [ICD-11 Extension code]
- Indinavir (substance) [SNOMED CT concept]
- Product containing indinavir (medicinal product) [SNOMED CT concept]
- indinavir [MeSH concept]
- indinavir [ATC Code]
- indinavir [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Indinavir [SMS substance]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Indinavir [NCIt concept]
is_component_of_chemotherapy_regimen
- Autologous Dendritic Cells/Indinavir [NCIt concept]
- Indinavir/Lamivudine/Stavudine [NCIt concept]
is_salt_form_of
- Indinavir [NCIt concept]

Keyword's position in hierarchy(ies) :

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