Indinavir - CISMeF

Preferred Label : Indinavir;

NCIt synonyms : IDV; Compound J; (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide; Indinavir Base;

NCIt definition : A synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2. The incorporation of a basic amine into the hydroxyethylene backbone improves its aqueous solubility and its oral bioavailability.;

Alternative definition : NCI-GLOSS: A drug that interferes with the ability of a virus to make copies of itself.;

UNII : 5W6YA9PKKH;

InChIKey : XTYSXGHMTNTKFH-BDEHJDMKSA-N;

CAS number : 180683-37-8;

Chemical formula : C36H47N5O4.H2O;

Codes from synonyms : CDR0000045520;

Details

Origin ID

C66877;

UMLS CUI

C0376637;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Indinavir [LOINC component]
- Indinavir (substance) [SNOMED CT concept]
- Product containing indinavir (medicinal product) [SNOMED CT concept]
- indinavir [ATC Code]
- indinavir [MeSH concept]
- indinavir [MeSH Descriptor]
Validated automatic mappings to BTNT
- indinavir [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Indinavir Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Indinavir Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

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