Buspirone - CISMeF

Preferred Label : Buspirone;

NCIt synonyms : Buspirone Base;

NCIt definition : An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.;

Alternative definition : NCI-GLOSS: A drug that is used to treat certain anxiety disorders. It belongs to the family of drugs called antianxiety agents.;

UNII : TK65WKS8HL;

InChIKey : QWCRAEMEVRGPNT-UHFFFAOYSA-N;

CAS number : 36505-84-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 36505-84-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C21H31N5O2;

ChEBI ID : CHEBI:3223;

Codes from synonyms : CDR0000302452;

Details

Origin ID

C62013;

UMLS CUI

C0006462;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Buspirone [ICD-11 Extension code]
- Buspirone (substance) [SNOMED CT concept]
- Product containing buspirone (medicinal product) [SNOMED CT concept]
- busPIRone [LOINC component]
- buspirone [ATC Code]
- buspirone [Substance BNPC]
- buspirone [MeSH concept]
- buspirone [MeSH Descriptor]
- buspirone [SNOMED Notion]
Validated automatic mappings to BTNT
- buspirone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Buspirone Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Buspirone Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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