Buspirone Hydrochloride

Preferred Label : Buspirone Hydrochloride;

NCIt synonyms : Buspirone;

NCIt definition : The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.;

UNII : 207LT9J9OC;

InChIKey : RICLFGYGYQXUFH-UHFFFAOYSA-N;

CAS number : 33386-08-2;

Chemical formula : C21H31N5O2.HCl;

ChEBI ID : CHEBI:3224;

Details

Origin ID

C26641;

UMLS CUI

C0700444;

Automatic exact mappings (from CISMeF team)
- Buspirone [ICHI extension code]
- buspirone [MeSH Descriptor]
- buspirone [ATC Code]
- buspirone [Substance BNPC]
Currated CISMeF NLP mapping
- Buspirone hydrochloride [Substance BNPC]
- Buspirone Hydrochloride [International Nonproprietary Name]
- Buspirone hydrochloride [SMS substance]
- Buspirone hydrochloride (substance) [SNOMED CT concept]
- buspirone hydrochloride [MeSH concept]
- buspirone hydrochlorine [SNOMED Notion]
See also inter- (CISMeF)
- Buspirone hydrochloride (product) [Inactive SNOMED CT concept]
- Product containing buspirone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Buspirone hydrochloride [Substance BNPC]
- Buspirone Hydrochloride [International Nonproprietary Name]
- Buspirone hydrochloride (product) [Inactive SNOMED CT concept]
- Buspirone hydrochloride (substance) [SNOMED CT concept]
- buspirone hydrochloride [MeSH concept]
- buspirone hydrochlorine [SNOMED Notion]
Validated automatic mappings to NTBT
- Buspirone [ICD-11 Extension code]
- Buspirone (substance) [SNOMED CT concept]
- busPIRone [LOINC component]
- buspirone [MeSH Descriptor]
- buspirone [Substance BNPC]
- buspirone [SNOMED Notion]
- buspirone [MeSH concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Buspirone [NCIt concept]
is_salt_form_of
- Buspirone [NCIt concept]

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